The PicoSpritzer® III is a self-contained rack-mountable system which supplies repeatable pressure pulses. Intracellular applications range from femtolitre ejections of RNA into 50µm diameter cells, up to nanolitre ejections into oocytes. Extracellular applications range from delivery of picolitre volumes of neuroactive substances to neurons during intracellular recording up to chemical stimulus delivery to complete organisms.
The heart of the PicoSpritzer is its special high speed valve offering precise control of ejection volumes and millisecond range ejection times. Although volumes ejected are linear with both pressure and time the pulse duration has a greater dynamic range with more accurate and reproducible settings. This pulse duration is likely to be changed frequently during the course of an experiment while once established, pressure settings will be changed relatively little on a daily basis.
The pulse duration is controlled by a 3-digit thumbwheel switchable to read in milliseconds, seconds or minutes. A pulse may be initiated from a front panel button, a remote push-button, footswitch or external TTL pulse.

PICOSPRITZER MODELS
Picospritzer III is available as a single or two channel unit each of which can be triggered independently. Single channel models have built-in second channel expansion capability so can be converted to two channel simply by addition of a second valve box with tubing and connectors.

* Pipette holders (and gaskets) are available for pipettes from 1.0mm to 2.0mm in 0.2mm increments (plus 1.5mm). The two XX’s in the part number should be replaced by the pipette glass size in 10ths of millimetres. For example, part number 050-0012-130-1 would be for 1.2mm outer diameter pipettes.